Stem Cell Therapy for Knee Pain in Orlando
Stem Cell Therapy for Knee Pain in Orlando
Medically reviewed by Kenny Chantasi, DO — Board Certified in Physical Medicine & Rehabilitation (PM&R) and Pain Medicine · Last updated July 20, 2026
THIS NOTICE MUST BE PROVIDED TO YOU UNDER FLORIDA LAW. This physician performs one or more stem cell therapies that have not yet been approved by the United States Food and Drug Administration. You are encouraged to consult with your primary care provider before undergoing any stem cell therapy.
If knee pain is changing how you walk, work, or sleep, you're not alone — and you have more options than surgery or a lifetime of pain pills. For many Orlando patients, stem cell therapy for knees has become a serious question worth exploring: a physician-administered, non-surgical approach that aims to support your body's own repair processes. This guide explains, honestly, how it works, who tends to benefit, what the evidence does and doesn't show, and how Florida law shapes the way it's delivered here in Orlando.
What "stem cell therapy for knees" actually means
Stem cell therapy uses cells capable of signaling, modulating inflammation, and supporting tissue repair. For knee pain, the goal is not to "grow a new knee" — it's to calm the inflammatory environment inside the joint and support the tissues that keep the knee moving comfortably.
In an orthopedic and pain-management setting, these cells are typically placed into or around the knee under image guidance so they reach the right target. It's an in-office procedure, usually completed in a single visit, and most people return to light daily activity soon afterward. It is a treatment tool — not a miracle — and it works best as part of a plan that includes evaluation, rehabilitation, and realistic goals.
Who might be a candidate?
Stem cell therapy is most often considered for people with:
Mild-to-moderate knee osteoarthritis and joint-related wear
Persistent knee pain that hasn't responded to rest, physical therapy, or anti-inflammatory measures
Nagging tendon or soft-tissue irritation around the knee
A desire to explore non-surgical options before considering joint replacement
It's not right for everyone. Very advanced "bone-on-bone" arthritis, active infection, certain cancers, and some other medical conditions can make you a poor candidate — which is exactly why a physician evaluation comes first. Regenerative medicine for knees is a decision made with a doctor, not from a website.
What to expect: from consultation to recovery
Your visit starts with a real evaluation — your history, an exam, and a review of any imaging — so we can confirm what's driving your pain and whether regenerative care is a reasonable fit. If it is, the procedure itself is usually quick, performed in-office, and guided by imaging for accuracy.
Afterward, some soreness at the treatment site for a few days is normal. Many patients ease back into activity within a week and follow a gradual return-to-motion plan. Because your body's repair response unfolds over time, improvements — when they occur — tend to develop over weeks to months rather than overnight. Results vary from person to person, and no honest provider can promise a specific outcome.
Stem cell therapy and Florida law
Florida has a specific framework for this care. Under Florida SB 1768 (2025), licensed physicians may administer stem cell therapies that are not yet FDA-approved — but only for orthopedic conditions, wound care, and pain management, which is where knee treatment falls.
The law also builds in patient protections. The stem cell product must be sourced from a facility that meets accreditation standards, the therapy must be administered by (or under the supervision of) a physician, and you must receive clear information and provide signed informed consent before moving forward. You'll also receive the Florida notice you see at the top of this page. We follow these requirements closely — not as a formality, but because transparency is the foundation of good medicine.
An honest word on FDA status
Here's the straight answer: at this time, the stem cell therapies used for orthopedic and pain conditions are not FDA-approved, and you should be cautious of any clinic that claims otherwise or promises a cure. The FDA has published a consumer alert explaining what is and isn't established about regenerative products, which we encourage every patient to read: FDA Consumer Alert on Regenerative Medicine Products.
We'd rather you make a fully informed choice than an overhyped one. That means being clear about what the science supports, what remains investigational, and where your knee fits in the picture.
How it compares to other non-surgical options
Stem cell therapy is one tool among several. Depending on your knee, we may discuss physical therapy, activity and weight strategies, bracing, PRP (platelet-rich plasma), or corticosteroid injections. Each has trade-offs, and the "best" option is the one matched to your diagnosis and goals — not a one-size-fits-all package. For many people, the real value of a consultation is simply understanding the full menu before choosing.
Frequently asked questions
Is stem cell therapy for knees painful?
Most patients describe brief discomfort during the procedure and some soreness for a few days afterward. It's typically well tolerated and done in-office.
How long until I might notice a difference?
Because it relies on your body's own repair response, changes generally develop over weeks to months. Some people notice earlier improvement; others less. Results vary and are never guaranteed.
Will it cure my arthritis?
No. Stem cell therapy is not a cure for osteoarthritis. The realistic goal is to reduce pain and support function so you can move more comfortably — which we'll define together based on your knee.
Is it legal in Florida?
Yes, for orthopedic and pain conditions, physician-administered stem cell therapy is permitted under Florida SB 1768 with proper sourcing, informed consent, and the required Florida notice.
How much does it cost?
Cost depends on your specific plan and is discussed transparently during your consultation, so there are no surprises before you decide.
Talk to an Orlando physician who'll be straight with you
If you're weighing your options for knee pain, a focused evaluation is the best next step. We'll tell you honestly whether regenerative care makes sense for your knee — and if it doesn't, we'll point you toward what does.
PrimeCellMed
2295 S Hiawassee Road, Suite 410, Orlando, FL 32835 (MetroWest · Veranda Park)
Mon–Fri, 10 AM–6 PM
Book a consultation: primecellmed.com
Explore related care: Pain Treatment · Regenerative Pain Management · Joint Pain
Learn more from trusted sources: OrthoInfo (AAOS): Knee Osteoarthritis · FDA Consumer Alert on Regenerative Medicine
Medical disclaimer: This article is for general educational purposes only and is not medical advice, nor a substitute for evaluation, diagnosis, or treatment by a qualified healthcare professional. Stem cell therapies discussed here are not FDA-approved, individual results vary, and no specific outcome is guaranteed. Always consult a licensed physician — and your primary care provider — before beginning any treatment.