Stem Cell Therapy for Knee Pain in Orlando: What to Know

THIS NOTICE MUST BE PROVIDED TO YOU UNDER FLORIDA LAW. This physician performs one or more stem cell therapies that have not yet been approved by the United States Food and Drug Administration. You are encouraged to consult with your primary care provider before undergoing any stem cell therapy.

Medically reviewed by Kenny Chantasi, DO — Board Certified in Physical Medicine & Rehabilitation (PM&R) and Pain Medicine · Last updated July 19, 2026

Chronic knee pain has a way of shrinking your world — the stairs you avoid, the walks you cut short, the workouts you gave up. If you are researching stem cell therapy for knee pain in Orlando, you are likely looking for something between living with it and replacing the joint. At PrimeCellMed, our approach is physician-led and honest: we explain what regenerative options can and cannot do, evaluate whether you are a good candidate, and build a plan around your actual diagnosis rather than a one-size-fits-all protocol.

What is regenerative therapy for the knee?

Stem cell therapy is an umbrella term for regenerative approaches that aim to support the body’s own repair processes in a damaged joint. In an orthopedic setting, these procedures are typically used as non-surgical options for knee pain from osteoarthritis, cartilage wear, or certain soft-tissue injuries. The goal is to reduce pain and improve function, not to grow a brand-new knee. Regenerative medicine for joints is an evolving field, and the evidence base is still developing. That is exactly why a careful, diagnosis-first evaluation matters more than marketing promises.

PRP vs. stem cell therapy: what is the difference?

PRP (platelet-rich plasma) concentrates the healing factors already in your blood and injects them into the joint; it is well-studied for certain knee conditions and is often a first-line regenerative option. Stem cell or cell-based procedures aim to deliver reparative cells to the area. Which makes sense, if either does, depends on your diagnosis, imaging, activity goals, and overall health. During your Orlando consultation we walk through the trade-offs rather than defaulting you into the most expensive option.

Stem cell therapy and Florida law

Here is something many Floridians do not realize: in 2025, Florida enacted a law that expressly allows licensed physicians (MD/DO) to offer stem cell therapies that are not yet FDA-approved, specifically for orthopedic conditions, wound care, and pain management. Knee pain falls squarely within orthopedic and pain-management care, so Florida patients have a physician-administered path that is not available in most states. The law comes with important patient protections, and we follow them: stem cells must be sourced from FDA-registered, accredited facilities that meet strict manufacturing and viability standards; you receive a signed informed consent covering the treatment’s nature, its lack of FDA approval, expected results, risks, benefits, and alternatives; and the required Florida notice above must accompany our advertising.

What does the evidence and the FDA actually say?

Being straight with you is part of good medicine. While Florida permits these therapies for the categories above, they remain not FDA-approved, and the FDA maintains a consumer alert on regenerative medicine products, including stem cells and exosomes. Research on regenerative treatments for knee osteoarthritis is promising in some areas and still maturing in others. A responsible clinic tells you where the science is solid, where it is preliminary, and what realistic results look like for your knee.

Am I a candidate?

Good candidates are often people with mild-to-moderate knee osteoarthritis or certain soft-tissue issues who want to explore non-surgical options before considering replacement, but candidacy is individual. A physician evaluation, including a review of your history and imaging, is the only way to know. Some people are better served by physical therapy, bracing, other interventional options, or, in advanced cases, surgical referral. We would rather tell you that honestly than sell you a procedure that will not help.

Why choose PrimeCellMed in Orlando

Our practice is built around a rehabilitation-minded, diagnosis-first philosophy. We combine regenerative options with a broader view of what is driving your pain, because the knee rarely acts alone. If your situation calls for it, we coordinate care across our pain treatment and regenerative pain management services. You get a physician’s judgment, not a sales pitch.

Frequently asked questions

Is stem cell therapy for knees a cure? No. Regenerative options aim to reduce pain and improve function; they do not regrow a new joint. Results vary, and not everyone is a candidate.

PRP or stem cell therapy, which is better for knees? It depends on your diagnosis and goals. PRP is well-studied and often a first-line regenerative option; a physician evaluation determines what fits you.

Is stem cell therapy for knees FDA-approved? Many cell-based products are not FDA-approved for orthopedic use. We discuss the current regulatory and evidence status transparently during your consultation.

Is stem cell therapy legal in Florida? Yes, a 2025 Florida law allows licensed physicians to offer non-FDA-approved stem cell therapies for orthopedic conditions, wound care, and pain management, with informed consent and accredited-facility sourcing.

How do I know if I am a candidate? Through an in-person evaluation of your history and imaging. Some patients are better served by other treatments, and we will tell you if that is the case.

Talk to a physician in Orlando

If you want an honest, physician-led assessment of your knee-pain options, regenerative or otherwise, PrimeCellMed can help. PrimeCellMed, 2295 S Hiawassee Road, Suite 410, Orlando, FL 32835 (MetroWest, Veranda Park), Monday to Friday 10 AM to 6 PM. Book at primecellmed.com.

Medical disclaimer: This article is for general educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Stem cell therapies for orthopedic and pain-management use are permitted under Florida law but are not FDA-approved; individual results and candidacy vary, and statements here are not a promise of any particular outcome. The Florida notice above is provided as required by law. Always consult a qualified healthcare provider before beginning any treatment.